Determining Nucleotide Content :: Sequence Analysis (Bioinformatics Toolbox)

Bioinformatics Toolbox

Determining Nucleotide Content

In this example you are interested in studying the human mitochondrial genome. While many genes that code for mitochondrial proteins are found in the cell nucleus, the mitochondrial has genes that code for proteins used to produce energy.

First research information about the human mitochondria and find the nucleotide sequence for the genome. Next, look at the nucleotide content for the entire sequence. And finally, determine open reading frames and extract specific gene sequences.

Use the MATLAB Help browser to explore the Web. In the MATLAB Command Window, type
```
web('http://www.ncbi.nlm.nih.gov/')
```
A separate browser window opens with the home page for the NCBI Web site.
Search the NCBI Web site for information. For example, to search for the human mitochondrion genome, from the Search list, select Genome, and in the for box, enter mitochondrion homo sapiens.

The NCBI Web search returns a list of links to relevant pages.
Select a result page. For example, click the link labeled NC_001807.
The MATLAB Help browser displays the NCBI page for the human mitochondrial genome.

Example: Sequence Statistics

Getting Sequence Information into MATLAB